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重要文件

274666

Sigma-Aldrich

百里香醌

≥98%

同義詞:

2-异丙基-5-甲基-1,4-苯醌

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About This Item

經驗公式(希爾表示法):
C10H12O2
CAS號碼:
分子量::
164.20
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

品質等級

化驗

≥98%

形狀

solid

技術

titration: suitable

顏色

yellow

bp

230-232 °C (lit.)

mp

45-47 °C (lit.)

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

CC(C)C1=CC(=O)C(C)=CC1=O

InChI

1S/C10H12O2/c1-6(2)8-5-9(11)7(3)4-10(8)12/h4-6H,1-3H3

InChI 密鑰

KEQHJBNSCLWCAE-UHFFFAOYSA-N

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一般說明

百里香醌 (TQ) 又称 2-异丙基-5-甲基-1,4-苯醌,存在于一种三斜晶型。为黑种子挥发油的生物活性成分。TQ 在体外体内均表现出抗炎、抗氧化和抗肿瘤作用。

應用

百里醌已用于抑制大肠杆菌ATP合酶和细胞生长。还用作药物治疗下肢坐骨神经和股肌的缺血再灌注损伤。
百里醌在临床前研究中可用作神经保护和抗惊厥药。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

219.2 °F - closed cup

閃點(°C)

104 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth
Ahmad Z
PLoS ONE, 10 (2015)
Regine Schneider-Stock et al.
Drug discovery today, 19(1), 18-30 (2013-09-05)
Thymoquinone (TQ), the main active constituent of black seed essential oil, exhibits promising effects against inflammatory diseases and cancer. TQ, modulates signaling pathways that are key to cancer progression, and enhances the anticancer potential of clinical drugs while reducing their
Sanjeev Banerjee et al.
Nutrition and cancer, 62(7), 938-946 (2010-10-07)
Thymoquinone (TQ) is the predominant bioactive constituent present in black seed oil (Nigella sativa) and has been tested for its efficacy against cancer. Here, we summarize the literature about TQ's molecular mechanism of action and its ability to induce apoptosis
Hanene Jrah-Harzallah et al.
European journal of cancer (Oxford, England : 1990), 49(5), 1127-1135 (2012-11-08)
We evaluated pre- and post-thymoquinone (TQ) treatment on 1,2-dimethyl-hydrazine (DMH)-induced oxidative stress during initiation and promotion of colon carcinogenesis. Wistar rats were induced with DMH (20mg/kg) for 10 or 20 weeks, and treated with TQ (5mg/kg). Following sacrifice, the colons
Hala Gali-Muhtasib et al.
The international journal of biochemistry & cell biology, 38(8), 1249-1253 (2005-11-30)
There has been growing interest in naturally occurring compounds with anti-cancer potential. Black seed is one of the most extensively studied plants. This annual herb grows in countries bordering the Mediterranean Sea and India. Thymoquinone (TQ) is the bioactive constituent

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