推薦產品
應用
金黄色葡萄球菌鞘氨醇酶已用于：
- 二甲胺四环素诱导大鼠皮层神经毒性的研究
- 血清样品中的鞘磷脂浓度测定
- 增强鞘磷脂酶活性，研究 PARK9 介导的外泌体生物发生
生化／生理作用
启动形成基于鞘磷脂的第二信使。激活MAPK（丝裂原活化蛋白激酶）和SAPKs（应激活化蛋白激酶）；由鞘磷脂生成神经酰胺。
细菌鞘磷脂酶在中性 pH 下具有活性。用于体外细胞培养时，它会水解质膜外叶上的鞘磷脂，并产生脂溶性神经酰胺。鞘磷脂酶是鞘磷脂酶/神经酰胺途径中的关键酶，与几种神经退行性疾病的发病机制有关。
單位定義
在pH 7.4和37℃条件下，1个单位将每分钟水解1.0 μmol TNPAL-鞘磷脂。
外觀
溶于含0.25 M磷酸盐缓冲液的50%甘油，pH 7.5
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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