P7123

Protein Kinase Cν (PKCν) Active human

recombinant, expressed in E. coli, ≥75% (SDS-PAGE), buffered aqueous glycerol solution

• 同義詞: PKD3, Protein Kinase C nu
• MDL號碼: MFCD07371119
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 重組細胞: expressed in E. coli
• 品質等級: 200
• 化驗: ≥75% (SDS-PAGE)
• 形狀: buffered aqueous glycerol solution
• 分子量: protein apparent mol wt ~142 kDa
• UniProt登錄號: O94806
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... PRKD3(23683)

描述

應用

Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 °C using a final concentration of 50 μM [³²P] ATP.

生化／生理作用

PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.

外觀

Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol

安全資訊

• 儲存類別代碼: 10 - Combustible liquids