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Key Documents

L9641

Sigma-Aldrich

脂多糖 来源于大肠杆菌 EH100(Ra 突变体)

同義詞:

LPS

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About This Item

EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

Escherichia coli (EH100 Ra mutant)

品質等級

形狀

lyophilized powder

雜質

<3% Protein (Lowry)

顏色

white to yellow

溶解度

water: 4.90-5.10 mg/mL, cloudy to turbid, colorless to faintly yellow

運輸包裝

ambient

儲存溫度

2-8°C

一般說明

本品是使用苯酚:氯仿:石油醚从大肠杆菌EH 100(Ra突变株)中提取的。来源菌株由私人提供。

生化/生理作用

脂多糖(LPS)位于无荚膜菌株的膜外层,暴露于细胞表面。它们有助于维持外膜的完整性,并防止胆汁盐和亲脂性抗生素破坏细胞。

準備報告

通过苯酚-氯仿-石油醚萃取进行制备。

本品可溶于水(5 mg/ml)或细胞培养基(1 mg/ml),产生混浊的淡黄色溶液。溶于生理盐水并涡旋和加热至70-80 oC后,可形成浓度更高但仍然混浊的溶液(20 mg/ml)。脂多糖分子可在各种溶剂中形成胶束。溶于水和磷酸盐缓冲盐水时,可观察到浑浊的溶液。使用有机溶剂不能形成更清晰的溶液。使用甲醇可产生具有漂浮物的混浊悬浮液,而溶于水会产生均匀的混浊溶液。

其他說明

为了全面了解我们针对客户研究提供的各种脂多糖产品,建议您访问我们的碳水化合物分类页面。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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存取文件庫

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Ji Hyung Kim et al.
PloS one, 7(9), e45348-e45348 (2012-10-03)
During interaction with APCs, invariant (i) NKT cells are thought to be indirectly activated by TLR4-dependently activated APCs. However, whether TLR4 directly activates iNKT cells is unknown. Therefore, the expression and function of TLR4 in iNKT cells were investigated. Flow
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Journal of the American Society of Nephrology : JASN, 30(9), 1573-1586 (2019-07-10)
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Kelly M DeMars et al.
Biochemical and biophysical research communications, 497(1), 410-415 (2018-02-16)
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