推薦產品
生物源
Escherichia coli (O26:B6)
品質等級
形狀
lyophilized powder
純化經由
gel-filtration chromatography
雜質
<5% Protein
顏色
white to faint yellow
溶解度
water: 4.90-5.10 mg/mL, cloudy to hazy, colorless to faintly yellow
運輸包裝
ambient
儲存溫度
2-8°C
尋找類似的產品？ 前往 產品比較指南
相關類別
一般說明
该产品是从大肠杆菌血清型 O26:B6中提取的，并已通过凝胶过滤进行纯化。源菌株是ATCC 12795。来自血清型 026的LPS：B6是来自大肠杆菌的唯一 LPS，其在SDS-PAGE 上表现出短链长行为。该 LPS的短链长度接近突变粗糙株 LPS的短链长。该LPS血清型已经以1 μg/ml用于刺激中性粒细胞。
應用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征成分。LPS及其脂质A部分通过Toll样受体4（TLR4）刺激先天免疫系统的细胞，TLR4是Toll样受体蛋白家族的成员，该家族可识别常见的病原体相关分子模式（PAMP）。
生化／生理作用
脂多糖（LPS）位于膜的外层，并且暴露在无包膜菌株的细胞表面。它们有助于维持外层膜的完整性，并保护细胞免受胆汁盐和亲脂性抗生素的破坏。
準備報告
本品溶于水(5 mg/ml)或细胞培养基（1 mg/ml），得到浑浊的淡黄色溶液。以盐水为溶剂时，经过涡旋并加热至70-80 oC后，得到浓度更高但仍然浑浊的溶液（20 mg/ml）。脂多糖分子可在各种溶剂中形成胶束。在水和磷酸盐缓冲盐水中，可观察到混浊的溶液。使用有机溶剂不会得到更澄清的溶液。以甲醇为溶剂将得到含漂浮物的混浊悬浮液，而以水为溶剂将得到均匀的混浊溶液。
相關產品
產品號碼
描述
訂價
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Antonina Akk et al.
Frontiers in immunology, 7, 325-325 (2016-09-13)
Paramyxoviral infection in childhood has been linked to a significant increased rate of asthma development. In mice, paramyxoviral infection with the mouse parainfluenza virus type I, Sendai virus (Sev), causes a limited bronchiolitis followed by persistent asthma traits. We have
Randy Tatt Yhew Haw et al.
Journal of neuroinflammation, 11, 134-134 (2014-07-31)
We report a novel method of culturing microglia in three dimension (3D) using collagen as a substrate. By culturing microglia within a matrix, we aim to emulate the physical state of microglia embedded within parenchyma. BV2 microglia cell suspensions were
Paula Bertram et al.
Monoclonal antibodies in immunodiagnosis and immunotherapy, 34(1), 1-6 (2015-02-28)
The complement alternative pathway (AP) is a major contributor to a broad and growing spectrum of diseases that includes age-related macular degeneration, atypical hemolytic uremic syndrome, and preeclampsia. As a result, there is much interest in the therapeutic disruption of
Huimin Yan et al.
Arteriosclerosis, thrombosis, and vascular biology, 36(8), 1660-1669 (2016-06-11)
We previously established that neutrophil-derived dipeptidyl peptidase I (DPPI) is essential for experimental abdominal aortic aneurysm (AAA) development. Because DPPI activates several neutrophil serine proteases, it remains to be determined whether the AAA-promoting effect of DPPI is mediated by neutrophil
Yosra Bedoui et al.
PLoS neglected tropical diseases, 12(8), e0006634-e0006634 (2018-08-04)
Chikungunya virus (CHIKV) is a mosquito-transmitted RNA alphavirus causing major outbreaks of infectious chronic inflammatory rheumatisms (CIR). Recently, methotrexate (MTX), a disease modifying anti-rheumatic drug has been used successfully to treat patients suffering from rheumatoid-like arthritis post-CHIK but its immunomodulatory
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務