推薦產品
生物源
Escherichia coli (O128:B12)
品質等級
形狀
lyophilized powder
純化經由
phenol extraction
雜質
<3% Protein (Lowry)
顏色
white to yellow cast
溶解度
water: soluble
運輸包裝
ambient
儲存溫度
2-8°C
尋找類似的產品? 前往 產品比較指南
相關類別
一般說明
该产物是从大肠杆菌血清型O128:B12中通过苯酚提取得到。源菌株为CDC 2440-69。
應用
脂多糖(LPS)是革兰氏阴性菌细胞壁的特征性成分。LPS及其脂质A部分可通过Toll样受体4(TLR4)刺激先天免疫系统细胞,TLR4是Toll样受体蛋白家族的成员,它能识别常见的病原体相关分子模式(PAMP)。
生化/生理作用
脂多糖(LPS)位于膜的外层,并且暴露在无包膜菌株的细胞表面。它们有助于维持外层膜的完整性,并保护细胞免受胆汁盐和亲脂性抗生素的破坏。
準備報告
本品溶于水(5 mg/ml)或细胞培养基(1 mg/ml),得到浑浊的淡黄色溶液。以盐水为溶剂时,经过涡旋并加热至70-80 oC后,得到浓度更高但仍然浑浊的溶液(20 mg/ml)。脂多糖分子可在各种溶剂中形成胶束。在水和磷酸盐缓冲盐水中,可观察到混浊的溶液。使用有机溶剂不会得到更澄清的溶液。以甲醇为溶剂将得到含漂浮物的混浊悬浮液,而以水为溶剂将得到均匀的混浊溶液。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
BMC immunology, 10, 49-49 (2009-09-22)
Previous reports indicate that ethanol, in a binge drinking model in mice, inhibits the production of pro-inflammatory cytokines in vivo. However, the inhibition of signaling through TLR4 has not been investigated in this experimental model in vivo. Considering evidence that
Beilstein journal of organic chemistry, 8, 763-775 (2012-09-28)
Two new triterpenoid saponins 1 and 2 were isolated from the methanol extract of the roots of Acanthophyllum gypsophiloides Regel. These saponins have quillaic acid or gypsogenin moieties as an aglycon, and both bear similar sets of two oligosaccharide chains
Molecular cell, 40(5), 787-797 (2010-12-15)
Endoplasmic reticulum (ER) oxidation 1 (ERO1) transfers disulfides to protein disulfide isomerase (PDI) and is essential for oxidative protein folding in simple eukaryotes such as yeast and worms. Surprisingly, ERO1-deficient mammalian cells exhibit only a modest delay in disulfide bond
PloS one, 10(11), e0142031-e0142031 (2015-11-05)
Given the role of infectious disease in global pollinator decline, there is a need to understand factors that shape pathogen susceptibility and transmission in bees. Here we ask how urbanization affects the immune response and pathogen load of feral and
Journal of applied toxicology : JAT, 34(12), 1436-1442 (2014-10-22)
Isoniazide (INH) is a classic antituberculosis drug associated with clinical idiosyncratic drug-induced liver injury. It has been hypothesized that the interaction between a drug and modest inflammation results in a decreased threshold for drug toxicity. In this study, we tested
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務