推薦產品
product name
鹅膏氨酸, ~95%, solid
化驗
~95%
形狀
solid
顏色
white
溶解度
H2O: 1 mg/mL, clear, colorless (with sonication)
0.1 M NaOH: 10.7 mg/mL
0.1 M HCl: 4.7 mg/mL
SMILES 字串
NC(C(O)=O)C1=CC(=O)NO1
InChI
1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
InChI 密鑰
IRJCBFDCFXCWGO-UHFFFAOYSA-N
基因資訊
rat ... Grm1(24414) , Grm2(24415)
尋找類似的產品? 前往 產品比較指南
應用
鹅膏蕈氨酸作为神经毒素用于大鼠。也可用于诱导猴大脑皮层M1神经元发生原发永久性病变。
鹅膏蕈氨酸被用于成年雄性斑胸草雀 ( Taeniopygia guttata ) 手术,以研究逆转增强剂诱导的发声变化。
生化/生理作用
对NMDA谷氨酸受体优先选择的非选择性激动剂;神经毒素。神经兴奋性氨基酸最初分离自鹅膏菌种。
鹅膏蕈氨酸是谷氨酸类似物。参与兴奋细胞体,破坏丘脑网状核(NRT)。它能诱导大量钙离子流入,导致神经元损伤。由于其具有兴奋性毒性功能,鹅膏蕈氨酸用于诱导产生神经退行性变。
注意
吸湿
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
PLoS biology, 16(4), e2002909-e2002909 (2018-04-14)
The rostromedial tegmental nucleus (RMTg), also called the GABAergic tail of the ventral tegmental area, projects to the midbrain dopaminergic system, dorsal raphe nucleus, locus coeruleus, and other regions. Whether the RMTg is involved in sleep-wake regulation is unknown. In
Intrahippocampal administration of ibotenic acid induced cholinergic dysfunction via NR2A/NR2B expression: Implications of resveratrol against Alzheimer disease pathophysiology
Frontiers in Molecular Neuroscience, 9, 28-28 (2016)
Brain structure & function, 222(9), 3899-3914 (2017-05-11)
Hippocampal damage in adult humans impairs episodic and semantic memory, whereas hippocampal damage early in life impairs episodic memory but leaves semantic learning relatively preserved. We have previously shown a similar behavioral dissociation in nonhuman primates. Hippocampal lesion in adult
eLife, 7 (2018-07-26)
Speech is a complex sensorimotor skill, and vocal learning involves both the basal ganglia and the cerebellum. These subcortical structures interact indirectly through their respective loops with thalamo-cortical and brainstem networks, and directly via subcortical pathways, but the role of
Journal of neuroscience methods, 275, 1-9 (2016-10-18)
Correlated neuronal activity in the brain is hypothesized to contribute to information representation, and is important for gauging brain dynamics in health and disease. Due to high dimensional neural datasets, it is difficult to study temporal variations in correlation structure.
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務