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重要文件

M104

Sigma-Aldrich

(±)-Muscarine chloride hydrate

≥98% (HPLC)

同義詞:

Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate

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About This Item

經驗公式(希爾表示法):
C9H20ClNO2 · xH2O
CAS號碼:
分子量::
209.71 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

white

溶解度

deionized water: ≥20 mg/mL

儲存溫度

room temp

SMILES 字串

[Cl-].CC1OC(CC1O)C[N+](C)(C)C

InChI

1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1

InChI 密鑰

WUFRNEJYZWHXLC-UHFFFAOYSA-M

應用

(±)-Muscarine chloride hydrate may be used:
  • as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
  • as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments
  • as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples

生化/生理作用

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.
Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

特點和優勢

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Chapter 67 - Mushroom Toxins
Puschner B
Veterinary Toxicology, 955-966 (2018)
P J FRASER
British journal of pharmacology and chemotherapy, 12(1), 47-52 (1957-03-01)
The action of chromatographically pure crystalline muscarine chloride, prepared from Amanita muscaria, has been compared with acetylcholine chloride (ACh) on a number of different organs from a variety of species. Muscarine caused spasm in vivo and in vitro of muscles

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