推薦產品
產品名稱
戊四唑,
形狀
powder
bp
194 °C/12 mmHg (lit.)
mp
59-61 °C (lit.)
儲存溫度
−20°C
SMILES 字串
C1CCc2nnnn2CC1
InChI
1S/C6H10N4/c1-2-4-6-7-8-9-10(6)5-3-1/h1-5H2
InChI 密鑰
CWRVKFFCRWGWCS-UHFFFAOYSA-N
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一般說明
戊四唑(PTZ)为四唑衍生物,是γ氨基丁酸(GABAA)及其受体复合物的抑制剂。 PTZ是用于诱发惊厥的惊厥剂。可穿透血脑屏障。
應用
戊四唑用于诱发斑马鱼幼虫 、小鼠 和雄性Wistar大鼠发生惊厥。
生化/生理作用
戊四唑是非特异性中枢神经系统(CNS)兴奋剂和惊厥剂。PTZ诱发氧化应激,增加皮质内丙二醛含量并影响海马体功能,导致发生惊厥。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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