C4024

卡马西平

≥98% (HPLC), powder, antiepileptic agent

• 同義詞: 5H-二苯并[b,f]氮杂-5-甲酰胺
• 經驗公式（希爾表示法）: C₁₅H₁₂N₂O
• CAS號碼: 298-46-4
• 分子量：: 236.27
• EC號碼: 206-062-7
• MDL號碼: MFCD00005073
• 分類程式碼代碼: 12352200
• eCl@ss: 34051404
• PubChem物質ID: 57654002
• NACRES: NA.77

屬性

• product name: 卡马西平, powder
• 形狀: powder
• 品質等級: 100
• mp: 191-192 °C (lit.)
• 溶解度: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL; H₂O: insoluble; ethanol: soluble; propylene glycol: soluble
• 起源: Novartis
• 儲存溫度: 2-8°C
• SMILES 字串: NC(=O)N1c2ccccc2C=Cc3ccccc13
• InChI: 1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
• InChI 密鑰: FFGPTBGBLSHEPO-UHFFFAOYSA-N
• 基因資訊: human ... BZRAP1(9256) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , PRNP(5621) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scn2a1(24766) , Scnn1a(25122) , Scnn1g(24768) , Slc6a1(79212)

描述

應用

Carbamazepine has been used to investigate its behavior in wastewater treatment and during groundwater infiltration. It has also been used to find out its effects on spontaneous seizures in rats.

生化／生理作用

Carbamazepine is considered as a safe antiepileptic drug. It decreases the multiple drug therapy and maintains a better control of epilepsy.

抗惊厥药；GABA_A受体苯二氮卓调节位点的配体。钠离子通道抑制剂。

特點和優勢

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H317,H334,H336,H360FD
• 防範說明: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• 危險分類: Acute Tox. 4 Oral - Repr. 1A - Resp. Sens. 1 - Skin Sens. 1A - STOT SE 3
• 標靶器官: Central nervous system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Faceshields, Gloves