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About This Item
經驗公式（希爾表示法）:
C17H18FN3O3
CAS號碼:
分子量：:
331.34
Beilstein:
3568352
MDL號碼:
分類程式碼代碼:
41116105
PubChem物質ID:
NACRES:
NA.21
推薦產品
agency
EPA 1694
品質等級
化驗
≥98% (HPLC)
形狀
powder or crystals
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
應用
environmental
作用方式
DNA synthesis | interferes
enzyme | inhibits
SMILES 字串
OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O
InChI
1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
InChI 密鑰
MYSWGUAQZAJSOK-UHFFFAOYSA-N
基因資訊
human ... CYP1A2(1544) , KCNH1(3756)
rat ... Gabra1(29705)
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相關類別
一般說明
环丙沙星是第二代广谱氟喹诺酮抗生素，具有广泛抗菌性和药动学特征，广泛用于对抗细菌感染。化学名称是1-环丙基-6-氟-4-氧代-7-(哌嗪-1-基)-1,4-二氢喹啉-3-羧酸。
化学结构：氟喹诺酮
化学结构：氟喹诺酮
應用
环丙沙星在临床中广泛用于对付革兰阳性和阴性菌，治疗皮肤、眼睛、泌尿道、下呼吸道、胃肠道等多个部位的感染。 还可联合多种抗菌药物对抗细菌生物膜和多重耐药微生物。另外，开发的衍生物可合成新型抗菌药物，疗效增强且具有抗菌、抗真菌、抗HIV、抗肿瘤和抗TB等各种抗微生物活性。
生化／生理作用
环丙沙星的作用机制是 通过抑制DNA促旋酶(gyrase)和影响细菌细胞壁来抑制细菌DNA合成 。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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