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About This Item
經驗公式（希爾表示法）:
C23H26N5NaO7S
CAS號碼:
分子量：:
539.54
Beilstein:
5373920
EC號碼:
MDL號碼:
分類程式碼代碼:
51282423
PubChem物質ID:
NACRES:
NA.85
推薦產品
品質等級
形狀
powder
溶解度
H2O: soluble 50 mg/mL
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
作用方式
cell wall synthesis | interferes
儲存溫度
2-8°C
SMILES 字串
[Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)c4ccccc4)C(=O)C1=O
InChI
1S/C23H27N5O7S.Na/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);/q;+1/p-1/t13-,14-,15+,20-;/m1./s1
InChI 密鑰
WCMIIGXFCMNQDS-IDYPWDAWSA-M
尋找類似的產品？ 前往 產品比較指南
一般說明
Chemical structure: ß-lactam
應用
Piperacillin is a semisynthetic, broad-spectrum ureidopenicillin antibiotic. It is derived from ampicillin. It has been used in pharmacokinetic studies in order to optimize antimicrobial therapy in patients with sepsis. It is used to study piperacillin hypersensitivity reactions and to study multidrug-resistant organisms.
生化／生理作用
Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.
包裝
1g,5g,10g
其他說明
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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Grace C Lee et al.
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Studies evaluating the outcomes of an extended-infusion (EI) piperacillin-tazobactam dosing strategy in specific cohorts of critically ill patients are lacking. A retrospective, pre-implementation and post-implementation study of 148 critically ill patients was conducted to compare EI and traditional infusion piperacillin-tazobactam.
Saloni Singla et al.
The Journal of antibiotics, 66(2), 61-66 (2012-11-22)
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Journal of immunology (Baltimore, Md. : 1950), 187(1), 200-211 (2011-05-25)
A mechanistic understanding of the relationship between the chemistry of drug Ag formation and immune function is lacking. Thus, mass spectrometric methods were employed to detect and fully characterize circulating Ags derived from piperacillin in patients undergoing therapy and the
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João Gonçalves-Pereira et al.
PloS one, 7(11), e49845-e49845 (2012-11-28)
The clinical efficacy of continuous infusion of piperacillin/tazobactam in critically ill patients with microbiologically documented infections is currently unknown. We conducted a retrospective multicenter cohort study in 7 Portuguese intensive care units (ICU). We included 569 critically ill adult patients
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