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重要文件

S9701

Sigma-Aldrich

舒巴坦酸

同義詞:

(2S,5R)-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸4,4-二氧化物, CP 45899, CP-45,899, 舒巴克坦, 青霉烷砜酸, 青霉酸1,1-二氧化物, 青霉酸二氧化物, 青霉酸砜

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About This Item

經驗公式(希爾表示法):
C8H11NO5S
CAS號碼:
分子量::
233.24
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

品質等級

形狀

powder

光學活性

[α]/D ≥+225°, c = 1 in H2O

顏色

white to tan

溶解度

H2O: ≥18 mg/mL

儲存溫度

2-8°C

SMILES 字串

CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O

InChI

1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1

InChI 密鑰

FKENQMMABCRJMK-RITPCOANSA-N

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一般說明

舒巴坦是一种半合成青霉素砜,来源于6-氨基青霉烷酸。这种β-内酰胺化合物的特征为具有一个 β-内酰胺环。

應用

舒巴坦可用作β-内酰胺酶抑制剂测试中的β-内酰胺酶抑制剂。 它也可用于评估其对极端耐药的鲍曼不动杆菌的抗菌药效学作用。舒巴坦可用于细胞信号转导研究。

生化/生理作用

舒巴坦为 β-内酰胺酶的不可逆抑制剂,可使β-内酰胺如青霉素和头孢菌素失活。它也可对拟杆菌和革兰氏阴性菌的某些染色体介导酶起作用。它具有有限的抗菌活性。 但是,舒巴坦与其它潜在抗生素的联合使用对多重耐药型鲍曼不动杆菌感染有治疗作用。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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