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C7039

Sigma-Aldrich

Cefotaxime sodium salt 钠盐

powder or crystals, suitable for plant cell culture, BioReagent

同義詞:

Cefotaxim sodium salt 钠盐

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About This Item

經驗公式(希爾表示法):
C16H16N5NaO7S2
CAS號碼:
分子量::
477.45
Beilstein:
5711411
EC號碼:
MDL號碼:
分類程式碼代碼:
10171502
PubChem物質ID:
NACRES:
NA.72

product name

Cefotaxime sodium salt 钠盐, suitable for plant cell culture, BioReagent, powder or crystals

產品線

BioReagent

形狀

powder or crystals

技術

cell culture | plant: suitable

顏色

off-white to pale yellow

溶解度

H2O: 10% ( )

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

應用

agriculture

作用方式

cell wall synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI 密鑰

AZZMGZXNTDTSME-JUZDKLSSSA-M

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一般說明

Chemical structure: ß-lactam

應用

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

生化/生理作用

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.
Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.

其他說明

Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


分析證明 (COA)

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Valeria Di Dato et al.
Scientific reports, 9(1), 9893-9893 (2019-07-11)
Diatoms are phytoplankton eukaryotic microalgae that are widely distributed in the world's oceans and are responsible for 20-25% of total carbon fixation on the planet. Using transcriptome sequencing here we show for the first time that the ubiquitous diatom Thalassiosira
Urinary Tract Infection in Children and Antimicrobial Resistance Pattern: Children UTI and Antibiotic Resistance (2019)
Metabolic profiling identifies trehalose as an abundant and diurnally fluctuating metabolite in the microalga Ostreococcus tauri
Hirth M, et al.
Metabolomics, 13(9), 68-68 (2017)
Anthony Ayodeji Adegoke et al.
Antimicrobial resistance and infection control, 9(1), 46-46 (2020-03-14)
The World Health Organization (WHO) recently classified Enterobacteriaceae resistance to third-generation cephalosporin into the group of pathogens with critical criteria for future research. A study to assess the antibiogram and beta-lactamase genes among the cefotaxime resistant E. coli (CREc) from
Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use.
AA C, et al.
Drugs (1983)

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