I0160

亚胺培南 一水合物

≥98% (HPLC)

• 同義詞: Primaxin 一水合物, Tienam 一水合物, （5R，6S）-6-[（（1R）-1-羟基乙基] -3-[[2-[（亚氨基甲基）氨基]乙基]硫代] -7-氧代-1-氮杂双环[3.2.0] hept-2 -烯-2-羧酸 一水合物
• 經驗公式（希爾表示法）: C₁₂H₁₇N₃O₄S · H₂O
• CAS號碼: 74431-23-5
• 分子量：: 317.36
• EC號碼: 264-734-5
• MDL號碼: MFCD09753321
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329815301
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +73 to +84°, c = 0.5 in water
• 顏色: white to beige
• 溶解度: H₂O: >5 mg/mL
• 抗生素活性譜: mycobacteria
• 作用方式: cell wall synthesis | interferes
• 起源: Merck & Co., Inc., Kenilworth, NJ, U.S.
• 儲存溫度: −20°C
• SMILES 字串: O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O
• InChI: 1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
• InChI 密鑰: GSOSVVULSKVSLQ-JJVRHELESA-N

描述

一般說明

Chemical structure: ß-lactam

應用

Imipenem monohydrate has been used to determine the resistance profiles of Pseudomonas aeruginosa isolates. It has also been used in susceptibility testing against Acinetobacter baumannii.

生化／生理作用

亚胺培南一水合物是广谱 B -内酰胺抗生素。

亚胺培南一水合物是广谱 B -内酰胺抗生素。 它是碳青霉烯类“魔弹”抗生素的一种，用于严重感染。

Imipenem is found effective against gram positive and negative aerobes and anaerobes. Imipenem is often combined with cilastatin, to inhibit its metabolism in kidney.

特點和優勢

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)