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重要文件

1134335

USP

环丙沙星盐酸盐

United States Pharmacopeia (USP) Reference Standard

同義詞:

环丙沙星 盐酸盐 一水合物

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About This Item

經驗公式(希爾表示法):
C17H18FN3O3 · HCl · H2O
CAS號碼:
分子量::
385.82
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

ciprofloxacin

製造商/商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

O.Cl.OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O

InChI

1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2

InChI 密鑰

ARPUHYJMCVWYCZ-UHFFFAOYSA-N

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一般說明

本产品按照发行药典的发行和规定提供。支持本产品的所有信息,包括安全数据表和任何产品信息传单,都是在发行药典的授权下开发和发布的。如需进一步信息和支持,请访问现行药典网站。

應用


  • 家禽中的抗菌应用:一项研究考察了患有蜂窝组织炎的肉鸡中的大肠杆菌分离菌株,重点介绍了环丙沙星治疗家禽细菌感染的作用,强调了其在农业抗生素应用中的有效性及其对动物健康的影响(Müller et al., 2024)。

  • 纳米载体药物递送:关于环丙沙星递送用pH敏感型纳米载体的研究讨论了壳聚糖-g-聚衣康酸基系统的开发,展示了先进的药物递送技术,这些技术可以提高环丙沙星等抗生素对耐药菌株的疗效(Kumar and Kumar, 2024

  • 光催化净化:一项光催化净化用Z构型异质结(Z-scheme heterojunction)中Fe-O-Bi电子迁移的研究强调了环丙沙星在主要用途之外的更广泛的应用,为药物污染物的环境管理提供了见解(Song et al., 2024)。

  • 牙髓学应用:一份关于牙髓病变在环丙沙星紧急治疗后非典型愈合的病例报告为其在牙科护理中的应用提供了宝贵数据,特别是对牙科手术后的感染管理有用(Asgary and Talebzadeh, 2024)。

  • 医院内感染:医院环境中耐甲氧西林金黄色葡萄球菌的基因组表征讨论了环丙沙星等抗生素在疫情控制中的作用,强调了分子研究在理解和管理医院内感染中的重要性(Huang et al., 2024)。

分析報告

这些产品仅供测试和化验使用。它们不适用于人类或动物,也不能用于诊断、治疗或治愈任何类型的疾病。

其他說明

可能适用相应的销售限制。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Andrea Meyerhoff et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 39(3), 303-308 (2004-08-13)
In August 2000, the US Food and Drug Administration (FDA) approved ciprofloxacin hydrochloride (Cipro; Bayer) for management of postexposure inhalational anthrax. This was the first antimicrobial drug approved by the FDA for use in treating an infection due to a
Lucile Pantel et al.
Antimicrobial agents and chemotherapy (2021-03-10)
NOSO-502 is a preclinical antibiotic candidate of the Odilorhabdin class. This compound exhibits activity against Enterobacteriaceae pathogens, including carbapenemase-producing bacteria and most of the Colistin (CST)-resistant strains. Among a collection of CST-resistant Klebsiella pneumoniae strains harboring mutations on genes pmrAB
Tarek Haddad et al.
Chemosphere, 115, 40-46 (2014-03-19)
The presence of pharmaceuticals, especially antibiotics, in the aquatic environment is of growing concern. Several studies have been carried out on the occurrence and environmental risk of these compounds. Ciprofloxacin (CIP), a broad-spectrum anti-microbial second-generation fluoroquinolone, is widely used in
Ziyu Sun et al.
Infection and immunity, 82(4), 1638-1647 (2014-02-05)
Pseudomonas aeruginosa is an opportunistic pathogen that causes acute and chronic infections in humans. Pyocins are bacteriocins produced by P. aeruginosa that are usually released through lysis of the producer strains. Expression of pyocin genes is negatively regulated by PrtR
Ting-Chi Yeh et al.
Cancer, 120(8), 1255-1262 (2014-01-15)
The purpose of the current study was to prevent bloodstream infection and invasive fungal infection (IFI) by administering prophylactic antibiotic and antifungal agents during intensive chemotherapy in patients being treated for acute leukemia. Prophylaxis treatment was administered during intensive chemotherapy

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