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Merck
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Key Documents

D7909

Sigma-Aldrich

Dicyclomine hydrochloride

≥99% (TLC), powder

同義詞:

2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride

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About This Item

經驗公式(希爾表示法):
C19H35NO2 · HCl
CAS號碼:
分子量::
345.95
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

化驗

≥99% (TLC)

形狀

powder

顏色

off-white

溶解度

H2O: 50 mg/mL

SMILES 字串

CCN(CCOC(C1(C2CCCCC2)CCCCC1)=O)CC.[Cl]

InChI

1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H

InChI 密鑰

GUBNMFJOJGDCEL-UHFFFAOYSA-N

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生化/生理作用

Competitive muscarinic acetylcholine receptor antagonist.

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Larissa Zeggio Perez Figueredo et al.
Brain research bulletin, 77(2-3), 71-76 (2008-06-28)
A number of studies have suggested that the glutamatergic and cholinergic systems are both involved in learning and memory processes and that they interact in order to facilitate these processes. However, the role of M1-muscarinic receptors in mediating this interaction
Najeeb-ur Rehman et al.
Phytotherapy research : PTR, 26(1), 136-141 (2011-10-19)
This study was aimed to provide the pharmacological basis for the medicinal use of Lepidium sativum in diarrhea using in vivo and in vitro assays. The seed extract of Lepidium sativum (Ls.Cr) at 100 and 300 mg/kg inhibited castor oil-induced diarrhea
Susan J Bartko et al.
Psychopharmacology, 214(2), 537-548 (2010-11-19)
Performance on the Cambridge Neuropsychological Test Automated Battery touchscreen paired-associates learning (PAL) test is predictive of Alzheimer's disease and impaired in schizophrenia and chronic drug users. An automated computer touchscreen PAL task for rats has been previously established. A pharmacologically
Christopher D Cox et al.
Journal of neurotrauma, 25(11), 1355-1365 (2008-12-09)
Recent studies indicate that alphaII-spectrin breakdown products (SBDPs) have utility as biological markers of traumatic brain injury (TBI). However, the utility of SBDP biomarkers for detecting effects of therapeutic interventions has not been explored. Acetylcholine plays a role in pathological
Z W Jiang et al.
Brain research, 852(1), 37-44 (2000-02-08)
The rat subdural hematoma (SDH) model produces a zone of ischemic brain damage within the hemisphere beneath the SDH. Previous studies have measured large increases in extracellular acetylcholine during cerebral ischemia in the rat. We examined infarct volume after selectively

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