PRNP
prion protein
同義詞:
ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30
物種:
Human PRNP (5621), Mouse Prnp (19122), Rat Prnp (24686), naked mole-rat Prnp (101710391), Domestic Rabbit PRNP (100345744), domestic guinea pig Prnp (100714701), cow PRNP (281427), sheep PRNP (493887), chicken PRNP (396452), dog PRNP (485783) ...更多
UniProtKB ID:
基因 ID:
- Human(5621) Summary: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
- Mouse(19122) prion protein
- Rat(24686) prion protein
- naked mole-rat(101710391) prion protein
- Domestic Rabbit(100345744) prion protein
- domestic guinea pig(100714701) prion protein
- cow(281427) prion protein
- sheep(493887) prion protein
- chicken(396452) prion protein
- dog(485783) prion protein
- Horse(100065904) prion protein
- domestic cat(493886) prion protein
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Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
抗朊病毒蛋白抗体，a.a.109-112，克隆3F4, clone 3F4, Chemicon®, from mouse,
物種活性
hamster, human
應用
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Prion Protein Antibody, Chemicon®, from mouse,
物種活性
bovine, elk, mouse, mule deer, sheep
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Prion Protein Antibody, NT, a.a. 78-97, serum, Chemicon®,
物種活性
human
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-淀粉样蛋白-β（低聚物）抗体，克隆F11G3, clone F11G3, from mouse,
物種活性
all, human, mouse
應用
ELISA
dot blot
immunofluorescence
immunoprecipitation (IP)
western blot
dot blot
immunofluorescence
immunoprecipitation (IP)
western blot
抗-Prion蛋白小鼠单克隆抗体, clone 8H4, purified from hybridoma cell culture,
物種活性
bovine, human, monkey, mouse, rat, sheep
應用
ELISA
electron microscopy
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
electron microscopy
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot