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About This Item
經驗公式（希爾表示法）:
C26H26N4O3
CAS號碼:
分子量：:
442.51
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推薦產品
品質等級
化驗
≥97%
形狀
powder
溶解度
DMSO: 10 mg/mL, clear
儲存溫度
−20°C
SMILES 字串
COc1ccc2n(CCCN(C)C)cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c2c1
InChI
1S/C26H26N4O3/c1-29(2)11-6-12-30-15-20(18-13-16(33-3)9-10-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-5-4-7-17(19)21/h4-5,7-10,13-15,27H,6,11-12H2,1-3H3,(H,28,31,32)
InChI 密鑰
LLJJDLHGZUOMQP-UHFFFAOYSA-N
應用
GO6983已作为蛋白激酶C（PKC）抑制剂，用以研究其对核输入的影响。它还用作Fc培养基中的补充剂，以在丝裂霉素C处理过的小鼠胚胎成纤维细胞（MEF）上培养小鼠胚胎干（mES）细胞。
生化／生理作用
蛋白激酶C（PKC）抑制剂选择性抑制几种 PKC 同工酶（PKCα和PKCβ的IC50=7nM；PKCγ 为6 nM；PKCδ 为10 nM；PKCζ 为60nM），但不抑制PKCμ（IC50=20 mM）。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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