推薦產品
應用
来自人红细胞（HCA）的碳酸酐酶已被用于研究碳酸酐酶（CA）的熔球态。分子伴侣样α-晶状体蛋白能够与这种状态的酶结合并阻止其聚集。 Sigma的酶已被用于分析酶的热力学稳定性。 此外，已经评估了该酶在人非小细胞肺癌中的临床意义。
生化／生理作用
碳酸酐酶是一种锌金属酶，其分子量约为30,000Da。该酶可以催化二氧化碳的水合，形成碳酸。它参与一些重要过程，如pH和CO2稳态、碳酸氢盐和CO2的转运、生物合成反应、骨吸收、钙化和致瘤性。因此，该酶是一个重要的抑制剂靶标，在青光眼、癫痫和帕金森氏病等各种病症中具有临床应用价值。
單位定義
在0 °C条件下，一Wilbur-Anderson (W-A)单位可使0.02M Trizma缓冲液pH在一分钟内从8.3降至 6.3。（一W-A单位基本上相当于一Roughton-Booth单位。）
準備報告
色谱
纯化的。
纯化的。
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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Enzymatic Assay of Carbonic Anhydrase for Wilbur-Anderson Units (EC 4.2.1.1)
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