推薦產品
生物源
synthetic
品質等級
化驗
≥99%
形狀
powder
pKa
7.2
mp
258-259 °C
溶解度
1 M NH4OH: 50 mg/mL
DMSO: soluble
methanol and ethanol: slightly soluble
SMILES 字串
CC(=O)Nc1nnc(s1)S(N)(=O)=O
InChI
1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
InChI 密鑰
BZKPWHYZMXOIDC-UHFFFAOYSA-N
基因資訊
human ... CA1(759) , CA12(771) , CA14(23632) , CA2(760) , CA3(761) , CA4(762) , CA5A(763) , CA5B(11238) , CA9(768)
mouse ... Car13(71934) , Car5a(12352)
rat ... Car2(54231) , Car4(29242)
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應用
乙酰唑胺已被用于：
- 研究其对脂肪变性肝移植物抗冷缺血再灌注损伤的保护作用{49）
- 通过盒式给药和快速平衡透析插入物，对其结合分离的猪视网膜色素上皮（RPE）黑色素的能力进行测定
- 验证用于发育毒性筛选测定的P19C5干细胞的体外成胃模型
- 通过酶动力学、体外、体内和计算机分析，研究在斑马鱼和A375人黑素瘤细胞中其对黑素生成的抑制作用
碳酸酐酶抑制剂；增加脑血流量。
生化／生理作用
乙酰唑胺是磺酰胺药物家族的成员之一。它具有抑制碳酸酐酶活性的能力。它能够迅速增加脑血流量（CBF），并作为一种研究工具用于CBF研究中。乙酰唑胺可作为癫痫、 青光眼和假瘤脑的治疗剂。
通过与水通道蛋白相互作用抑制膜的水渗透性
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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