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Key Documents

C130

Sigma-Aldrich

氯-APB 氢溴酸盐

solid

同義詞:

(±)-6-氯-7,8-二羟基-3-烯丙基-1-苯基-2,3,4,5-四氢-1H-3-苯并氮杂卓 氢溴酸盐, (±)-SKF-82958 氢溴酸盐, 6-氯-N-烯丙基-SKF-38393 氢溴酸盐

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About This Item

經驗公式(希爾表示法):
C19H20ClNO2 · HBr
CAS號碼:
分子量::
410.73
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

形狀

solid

顏色

tan

溶解度

H2O: 3.7 mg/mL
aqueous base: unstable
ethanol: soluble

儲存溫度

2-8°C

SMILES 字串

Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3

InChI

1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H

InChI 密鑰

WLXGFAVTAAQOFH-UHFFFAOYSA-N

基因資訊

human ... DRD1(1812)

應用

氯-APB氢溴酸盐用于药理学刺激D1多巴胺受体,研究其对小鼠脂肪量和肥胖相关蛋白(FTO)缺陷多巴胺D1受体表达的中刺状神经元(D1 MSN)运动反应的影响。

生化/生理作用

氯-APB氢溴酸盐又名SKF 82958,是一种D1多巴胺受体激动剂。D1受体激动剂预防和逆转芬太尼诱导的呼吸抑制,而不损害猫的阿片类镇痛作用。

注意

光敏性

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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