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About This Item
經驗公式（希爾表示法）:
C10H21NO4
CAS號碼:
分子量：:
219.28
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.32
推薦產品
產品名稱
N-Butyldeoxynojirimycin, film (dried in situ)
化驗
≥98% (TLC)
品質等級
形狀
film (dried in situ)
溶解度
water: 9.80-10.20 mg/mL, clear, colorless
儲存溫度
2-8°C
SMILES 字串
CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI
1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
InChI 密鑰
UQRORFVVSGFNRO-UTINFBMNSA-N
基因資訊
human ... UGCG(7357)
一般說明
N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.
應用
N-Butyldeoxynojirimycin has been used:
- in the inhibition of glycolipid synthesis in neuroblastoma cells
- in the inhibition the ceramide-specific glycosyltransferase in hepatocytes
- in the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.
生化／生理作用
α-glucosidase Inhibitor
N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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