描述
α-glucosidase substrate
品質等級
化驗
≥98% (TLC)
形狀
powder
溶解度
DMSO: 50 mg/mL, clear, colorless to faintly yellow
螢光
λex 316 nm; λem 375 nm (Reaction product)
λex 317 nm; λem 374 nm (pH9.0)
λex 360 nm; λem 449 nm
λex 365 nm; λem 445 nm in 0.1 M Tris pH 8.0 (α-glucosidase)
儲存溫度
−20°C
SMILES 字串
CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12
InChI
1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/m1/s1
InChI 密鑰
YUDPTGPSBJVHCN-JZYAIQKZSA-N
尋找類似的產品? 前往 產品比較指南
一般說明
4-甲基伞形酮α-D-吡喃葡萄糖苷是 α -葡萄糖苷酶的荧光底物。 4-甲基伞形酮α-D-吡喃葡萄糖苷,又称 4MU- α-glc,反应后生成产物 4MU,其荧光光谱峰值为 440nm。
應用
4-甲基伞形酮α-D-吡喃葡萄糖苷可作为荧光底物,用于α-D-葡萄糖苷酶的鉴别、表征和动力学分析。4-甲基伞形酮α-D-吡喃葡萄糖苷用于高通量筛选实验。它适用于肾脏及白细胞的庞佩氏症诊断。
包裝
无底玻璃瓶。内容物在插入的熔锥内。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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Fresenius Journal of Analytical Chemistry, 327, 521-521 (1987)
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The high frequency (3.3-3.9%) of acid α-glucosidase pseudodeficiency, c.[1726G>A; 2065G>A] homozygote (AA homozygote), in Asian populations complicates newborn screening for Pompe disease (glycogen storage disease type II or acid maltase deficiency) on dried blood spots, since AA homozygotes have a
Clinical genetics, 13(6), 504-510 (1978-06-01)
The diagnosis of Pompe's disease by the assay of acid alpha-glucosidase in kidney and leucocytes was not previously possible because of the presence of another component which had activity at pH 4.0, but was not deficient in the disease. This
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Journal of clinical neuromuscular disease, 9(4), 421-431 (2008-06-06)
Pompe disease, or glycogen storage disease type II, is a rare autosomal recessive disorder caused by mutations in the gene that encodes for alpha-glucosidase. Presentation in infancy is associated with respiratory failure, cardiomyopathy, and severe muscle weakness. Juvenile- or adult-onset
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