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Merck
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重要文件

465119

Sigma-Aldrich

黄芩素

98%

同義詞:

5,6,7-三羟基黄酮

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About This Item

經驗公式(希爾表示法):
C15H10O5
CAS號碼:
分子量::
270.24
Beilstein:
272683
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

solid

mp

256-271 °C (lit.)

官能基

ketone
phenyl

SMILES 字串

Oc1cc2OC(=CC(=O)c2c(O)c1O)c3ccccc3

InChI

1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H

InChI 密鑰

FXNFHKRTJBSTCS-UHFFFAOYSA-N

基因資訊

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一般說明

黄芩素是黄酮类化合物,是黄嘌呤氧化酶抑制剂。研究了黄芩素在人外周白细胞中的抗炎作用。

應用

黄芩素曾用于研究脂氧合酶的体外定量抑制。

生化/生理作用

尼泊尔和中日天然药中的黄酮类成分。 黄芩素是黄芩的主要黄酮,可抑制花生四烯酸代谢的12-脂氧合酶(12-LOX)途径,该途径可抑制癌细胞增殖并诱导细胞凋亡。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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文章

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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