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![反式-2-[3-(4-叔丁基苯基)-2-甲基-2-亚丙烯基]丙二腈 matrix substance for MALDI-MS, ≥99.0% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/249/587/f8021369-f65a-413d-887d-3c8a4d2a248f/640/f8021369-f65a-413d-887d-3c8a4d2a248f.png)
品質等級
化驗
≥99.0% (sum of DHB and 2-hydroxy-5-methoxybenzoic acid, HPLC)
≥99.0%
分析物功能類別
polymers
分析物化學類別
glycans, peptides, proteins
技術
MALDI-MS: suitable
溶解度
methanol: 1%, clear
正離子痕跡
Ca: ≤5 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤5 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
適合性
suitable for matrix substance for MALDI-MS
一般說明
“super-DHB”基质由2,5-DHB和2-羟基-5-甲氧基苯甲酸的混合物[9：1（w / w）]组成，该混合比例经验证为最有效的。2-羟基-5-甲氧基苯甲酸添加剂的有益效果归因于无序的2,5-DHB晶格，从而导致离子解吸增强（即“更软”解吸）和内部能量降低，这反过来导致亚稳碎裂的减少。据报道，对于标准葡聚糖混合物来说，其灵敏度可增加高达2至3倍，并伴随着增强的分辨率，其原因是亚稳离子形成的减少。另有报道表明，super-DHB基质可在胰蛋白酶糖肽中产生增强的信号。使用super-DHB基质可减少基质背景离子的存在，并导致聚糖信号在质谱中表现出更好的信噪比和更高的分辨率。
應用
- Glycan and Protein Analysis of Glycoengineered Bacterial E. coli Vaccines by MALDI-in-Source Decay FT-ICR Mass Spectrometry: This study demonstrates the application of Super-DHB as a matrix in advanced mass spectrometry for the detailed characterization of glycoengineered vaccines, essential for researchers in pharmaceuticals and life science manufacturing (Nicolardi et al., 2022).
- An Improved Method for Rapid Detection of Mycobacterium abscessus Complex Based on Species-Specific Lipid Fingerprint by Routine MALDI-TOF: Highlights the use of Super-DHB in enhancing the lipid fingerprinting capabilities of MALDI-TOF mass spectrometry, critical for rapid microbial identification in medical microbiology and pharmaceutical research (Jia Khor et al., 2021).
- Discrimination of bovine milk from non-dairy milk by lipids fingerprinting using routine matrix-assisted laser desorption ionization mass spectrometry: Illustrates the role of Super-DHB in differentiating dairy and non-dairy milks based on lipid profiles using MALDI-MS, vital for food scientists and chemists in quality control and food safety (England et al., 2020).
包裝
无底玻璃瓶。内含物在插入的融合锥体内。
分析報告
DHB和2-羟基-5-甲氧基苯甲酸的混合物（9：1）
相關產品
產品號碼
描述
訂價
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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