32417

那他霉素

VETRANAL^®, analytical standard

• 同義詞: 游霉素, 那他霉素
• 經驗公式（希爾表示法）: C₃₃H₄₇NO₁₃
• CAS號碼: 7681-93-8
• 分子量：: 665.73
• EC號碼: 231-683-5
• MDL號碼: MFCD00135085
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329754196
• 酶號碼: E235
• NACRES: NA.24

屬性

• 等級: analytical standard
• 品質等級: 100
• 產品線: VETRANAL^®
• 儲存期限: limited shelf life, expiry date on the label
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: cleaning products; cosmetics; food and beverages; personal care
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: C[C@@H]1C\C=C\C=C\C=C\C=C\[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3\C=C\C(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O
• InChI: 1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1
• InChI 密鑰: NCXMLFZGDNKEPB-FFPOYIOWSA-N

描述

一般說明

Natamycin is a polyene antibiotic that generally finds application as an antifungal agent as it lacks development of resistance and has a broad spectrum of activity. However, its mode of action is yet unclear, direct binding and isothermal titration calorimetry studies has revealed that natamycin binds specifically to ergosterol present in model membranes.

Natamycin shows activity against both molds and yeasts. It finds applications as a fungicidal and antibiotic preservative in the food industry.

應用

Natamycin may be used as an analytical reference standard for the quantification of the analyte in wine samples using high-performance liquid chromatography coupled to electrospray ionization in positive mode high resolution mass spectrometry (HPLC-ESI-HR-MS) and reversed-phase high-performance liquid chromatography-tandem mass spectrometry technique (UHPLC-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化／生理作用

与麦角固醇特异性结合并阻止真菌生长的抗真菌多烯大环内脂。但不同于制霉菌素和菲律宾菌素不同，那他霉素不会改变细胞质膜的渗透性

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3