P9703

游霉素

from Streptomyces chattanoogensis, ≥95% (HPLC)

• 同義詞: 那他霉素
• 經驗公式（希爾表示法）: C₃₃H₄₇NO₁₃
• CAS號碼: 7681-93-8
• 分子量：: 665.73
• EC號碼: 231-683-5
• MDL號碼: MFCD00135085
• 分類程式碼代碼: 51102829
• PubChem物質ID: 24899055
• NACRES: NA.85

屬性

• 生物源: Streptomyces chattanoogensis
• 品質等級: 300
• 化驗: ≥95% (HPLC)
• 形狀: lyophilized powder; powder
• 溶解度: 0.1% formic acid in methanol: soluble 1 mg/mL
• 抗生素活性譜: fungi
• 應用: agriculture; environmental
• 作用方式: cell membrane | interferes
• 儲存溫度: 2-8°C
• SMILES 字串: C[C@@H]1C\C=C\C=C\C=C\C=C\[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3\C=C\C(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O
• InChI: 1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1
• InChI 密鑰: NCXMLFZGDNKEPB-FFPOYIOWSA-N

描述

一般說明

Chemical structure: macrolide

應用

Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. Pimaricin is used as a fungicide in agar media. It is used to study the pleitropic regulator AdpAch and the gamma-butyrolactone regulatory system of Streptomyces chattanoogensis.

生化／生理作用

与麦角固醇特异性结合并阻止真菌生长的抗真菌多烯大环内脂。但不同于制霉菌素和菲律宾菌素不同，那他霉素不会改变细胞质膜的渗透性

其他說明

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8 °C. Light sensitive.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)