推薦產品
product name
伏立康唑, ≥98% (HPLC)
化驗
≥98% (HPLC)
形狀
powder
顏色
white
溶解度
DMSO: >20 mg/mL
儲存溫度
room temp
SMILES 字串
C[C@@H](c1ncncc1F)[C@](O)(Cn2cncn2)c3ccc(F)cc3F
InChI
1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1
InChI 密鑰
BCEHBSKCWLPMDN-MGPLVRAMSA-N
尋找類似的產品？ 前往 產品比較指南
一般說明
Voriconazole is a triazole and a synthetic derivative of fluconazole.
應用
Voriconazole has been used:
- as a control and Erg11 inhibitor in YPD medium
- as a reference drug to test the activity of essential oils against clinical strains of Candida sp.
- as an antifungal agent to test its interactions with valproic acid (VPA)
- to compare its in vitro antifungal activity with essential oils and its components against Cryptococcus neoformans azole-susceptible and not-susceptible clinical isolates
生化／生理作用
伏立康唑是用于治疗严重真菌感染的抗真菌药。伏立康唑通过抑制 CYP450 依赖性 14-α甾醇脱甲基酶来抑制麦角固醇合成，从而导致真菌细胞膜中的麦角固醇减少。
Voriconazole is used to treat invasive aspergillosis (IA). It is vigorous against Candida species, including the strains of Candida albicans, which shows resistance to fluconazole.
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - STOT RE 1 - STOT RE 2 Oral - STOT SE 2 Oral
標靶器官
Eyes, Liver,Kidney
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Use of Pinus sylvestris L.(Pinaceae), Origanum vulgare L.(Lamiaceae), and Thymus vulgaris L.(Lamiaceae) essential oils and their main components to enhance itraconazole activity against azole susceptible/not-susceptible Cryptococcus neoformans strains
Scalas D, et al.
BMC Complementary and Alternative Medicine, 18(1), 143-143 (2018)
Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents
Richie D L, et al.
Antimicrobial agents and chemotherapy, 57(5), 2272-2280 (2013)
pH-dependant antifungal activity of valproic acid against the human fungal pathogen Candida albicans
Chaillot J, et al.
Frontiers in Microbiology, 8, 1956-1956 (2017)
Voriconazole and posaconazole therapeutic drug monitoring: a retrospective study
Whitley M Y, et al.
Annals of Clinical Microbiology and Antimicrobials, 16(1), 60-60 (2017)
Liquid and vapour-phase antifungal activities of essential oils against Candida albicans and non-albicans Candida
Mandras N, et al.
BMC Complementary and Alternative Medicine, 16(1), 330-330 (2016)
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務