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Key Documents

791643C

Avanti

18:0-d35 Lyso PC

Avanti Research - A Croda Brand

同義詞:

1-油酰基(d7)-2-羟基-sn -甘油基-3-磷酸胆碱

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About This Item

經驗公式(希爾表示法):
C26H45D7NO7P
CAS號碼:
分子量::
528.71
分類程式碼代碼:
41141825
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (791643C-1mg)

製造商/商標名

Avanti Research - A Croda Brand

濃度

1 mg/mL (791643C-1mg)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

18:1-d7 Lyso PC 1油酰基(d7)-2-羟基-sn-甘油-3-磷酸胆碱是氘代磷脂。该脂质溶血磷脂酰胆碱是以油酸酯化。油酸包含氘离子。溶血磷脂酰胆碱(LPC) 是在磷脂酶 A2 的作用下由磷脂酰胆碱衍生而来。
这种氘标记的脂质也可用于多种脂质标准品制剂中。SPLASH LIPIDOMIX 标准品包括与人血浆的所有主要脂质类别对应的脂质,从而实现一种简单的内标溶液适用每种样品。

應用

18:1-d7 Lyso PC 已用于:
  • 作为高效液相色谱电喷雾电离串联质谱(HPLC-ESIMS/MS) 的内标物,用于来源于骨髓的巨噬细胞的脂质组学分析
  • 作为提取溶剂的成分,用于从生物样品中分离脂质
  • 作为液相色谱串联质谱(LC-MS/MS)中血清样品的内标物

生化/生理作用

溶血磷脂酰胆碱(LPC)。LPC 水平升高与糖尿病和心血管疾病有关。LPC 刺激细胞因子并与过敏性疾病有关。它还导致膜上的裂解。

包裝

5 mL透明玻璃密封安瓿(791643C-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Shayne A Snider et al.
The Journal of biological chemistry, 293(29), 11600-11611 (2018-06-09)
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and respond to danger and damage signals. Although it is well-known that energy metabolism can dictate macrophage
Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using

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