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Key Documents

791638C

Avanti

15:0-18:1-d7-PE

Avanti Research - A Croda Brand

同義詞:

1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺

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About This Item

經驗公式(希爾表示法):
C38H67D7NO8P
CAS號碼:
分子量::
711.01
分類程式碼代碼:
41141825
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (791638C-1mg)

製造商/商標名

Avanti Research - A Croda Brand

濃度

1 mg/mL (791638C-1mg)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

15:0-18:1-d7-PE (1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺)是氘代磷脂。该脂质包括与十五烷酸和油酸相连的磷脂酰乙醇胺。油酸为氘离子提供庇护。磷脂酰乙醇胺是一种膜磷脂,在其他甘油磷脂合成中充当中间体。
这种氘标记脂质也可在多种脂质标准的配方中获得。SPLASH LIPIDOMIX标准品包括与人血浆的所有主要脂质类别对应的脂质,从而实现一种简单的内标溶液适用每种样品。

應用

15:0-18:1-d7-PE (1-十五酰基-2-油酰基(d7)-sn-丙三基-3-磷酸乙醇胺)已用于:
  • 作为生物样品中脂质分离的萃取溶剂组分
  • 作为液相色谱串联质谱法(LC-MS/MS)测定血清样品的内部标准品
  • 作为傅立叶变换质谱(FTMS)分析中刺穿血浆样品的内部标准品

生化/生理作用

磷脂酰乙醇胺(PE)调节蛋白质折叠、蛋白质修饰、自噬和细胞分裂。PE作为糖基磷脂酰肌醇锚定蛋白(GPI-AP)合成的底物。低水平的PE可见于帕金森病,也可抑制蛋白质成熟。

包裝

2 mL棕色玻璃密封安瓿(791638C-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Michael S Gardner et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1118-1119, 137-147 (2019-04-30)
Progress toward better diagnosis and treatment of lipid metabolism-related diseases requires high throughput approaches for multiplexed quantitative analysis of structurally diverse lipids, including phospholipids (PLs). This work demonstrates a simplified "one-pot" phospholipid extraction protocol, as an alternative to conventional liquid-liquid
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
Dhaval Patel et al.
Oxidative medicine and cellular longevity, 2017, 4829180-4829180 (2017-08-09)
Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cells. PE comprises about 15-25% of the total lipid in mammalian cells; it is enriched in the inner leaflet of membranes, and it is especially abundant in the inner mitochondrial
Luce Farine et al.
Scientific reports, 5, 16787-16787 (2015-11-19)
Phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are among the most abundant phospholipids in biological membranes. In many eukaryotes, the CDP-ethanolamine and CDP-choline branches of the Kennedy pathway represent major and often essential routes for the production of PE and PC, with

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