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重要文件

A68203

Sigma-Aldrich

6-氨基烟酰胺

99%

同義詞:

6AN, 6-氨基-3-吡啶甲酰胺

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About This Item

經驗公式(希爾表示法):
C6H7N3O
CAS號碼:
分子量::
137.14
Beilstein:
116042
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

powder

mp

245-248 °C (lit.)

SMILES 字串

NC(=O)c1ccc(N)nc1

InChI

1S/C6H7N3O/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H2,7,9)(H2,8,10)

InChI 密鑰

ZLWYEPMDOUQDBW-UHFFFAOYSA-N

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一般說明

6-氨基烟酰胺是氨基吡啶,为特异性戊糖抑制剂,抑制 NADP产生。

應用

6-氨基烟酰胺可作为以下应用的反应物:
  • 合成6-取代的咪唑并[1,2-a吡啶,此产物有可能作为化学治疗药物。
  • 脱水 N-单苄基化过程。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges


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分析證明 (COA)

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A borrowing hydrogen methodology: palladium-catalyzed dehydrative N-benzylation of 2-aminopyridines in water.
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Dahan-Farkas N, et al.
European Journal of Medicinal Chemistry, 46(9), 4573-4583 (2011)
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Neutrophils kill ingested pathogens by the so-called oxidative burst, where reactive oxygen species (ROS) are produced in the lumen of phagosomes at very high rates (mM/s), although these rates can only be maintained for a short period (minutes). In contrast
Electrocatalytic synthesis of 6-aminonicotinic acid at silver cathodes under mild conditions.
Gennaro A, et al.
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PLoS pathogens, 13(9), e1006632-e1006632 (2017-09-19)
Monocytes are innate immune cells that play a pivotal role in antifungal immunity, but little is known regarding the cellular metabolic events that regulate their function during infection. Using complementary transcriptomic and immunological studies in human primary monocytes, we show

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