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719919

Sigma-Aldrich

Resomer® RG 752 H，聚（D,L-丙交酯-co-乙交酯）

acid terminated, lactide:glycolide 75:25, Mw 4,000-15,000

同義詞:

RESOMER® RG 752 H, PLGA

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About This Item

線性公式:
[C3H4O2]x[C2H2O2]y
CAS號碼:
26780-50-7
MDL號碼:
MFCD00131930
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

(Powder or Solid or Chunk(s))

饋電比

lactide:glycolide 75:25

分子量

Mw 4,000-15,000

降解時間

<6 months

雜質

≤0.1% Sulfated Ash (CONF0010 Conforms)

黏度

0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

轉變溫度

Tg 42-46 °C

儲存溫度

2-8°C

SMILES 字串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI 密鑰

LCSKNASZPVZHEG-UHFFFAOYSA-N

相關類別

一般說明

聚（D, L-丙交酯-co-乙交酯）（PLGA）是一种可生物降解和生物可吸收的聚合物，广泛用于可植入和可注射药物递送系统的配方中。PLGA材料可在体内诱导极小的炎症反应，并降解产生生物相容性乳酸和乙醇酸。

法律資訊

Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH

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儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
BCCH1655
BCCG6649
BCCG0691
BCCD3971
BCCC5679

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Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
Mani Gajendiran et al.
Colloids and surfaces. B, Biointerfaces, 104, 107-115 (2013-01-10)
A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles
Igor Jeroukhimov et al.
Journal of the American College of Surgeons, 218(1), 102-107 (2013-11-12)
Chronic pain after inguinal hernia repair occurs in 16% to 62% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for the procedure. We hypothesize that nonabsorbable sutures
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相關內容

RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

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