跳轉至內容
Merck
全部照片(3)

重要文件

P2066

Sigma-Aldrich

聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide 65:35, Mw 40,000-75,000

同義詞:

Lactel® B6001-1, PLGA

登入查看組織和合約定價


About This Item

線性公式:
[C3H4O2]x[C2H2O2]y
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

形狀

pellets

品質等級

饋電比

lactide:glycolide 65:35

分子量

Mw 40,000-75,000

儲存溫度

−20°C

SMILES 字串

OCC(O)=O.CC(O)C(O)=O

InChI

1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)

InChI 密鑰

XBBVURRQGJPTHH-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

應用


  • 吸入巨噬细胞凋亡体-工程微粒可构建促退行性微环境以对抗小鼠缺氧性肺损伤。:这项研究展示了利用聚(D,L-乳酸-共-乙醇酸)(PLGA)工程微粒在缺氧条件下促进肺组织再生的方法,凸显了其在开发先进的呼吸道损伤治疗策略方面的潜力(Liu et al., 2024)。

  • 工程纳米颗粒促进了AAV向量对心脏的滋养。:该研究探讨了PLGA纳米颗粒在提高AAV载体对心脏组织的靶向效率方面的作用,展示了其在基因治疗和心血管疾病治疗中的应用(Switala et al., 2024)。

  • 用于预防口腔表面生物膜的载药粘合微粒。:这篇文章报道了为防止口腔表面生物膜形成而设计的药物负载 PLGA 微颗粒的开发情况,展示了这种聚合物在牙科应用和生物膜相关感染中的实用性(Oh et al., 2024)。

  • 含有VEGF-A-转染Schwann细胞的双层导管通过血管生成促进周围神经再生。:基于PLGA的双层导管可通过增强血管生成来支持神经再生,这表明了它在神经再生医学和周围神经损伤治疗中的重要性(Huang et al., 2024)。

  • 在模拟黑色素瘤和皮肤鳞状细胞癌的三维人体皮肤模型上应用负载多柔比星的PLGA纳米粒子,靶向肿瘤细胞和癌症相关成纤维细胞。:该研究强调了聚乳酸乙二醇(PLGA)纳米颗粒在向肿瘤细胞和周围支持基质输送化疗药物方面的双重靶向能力,突出了其在晚期癌症疗法中的作用(He et al., 2024)。

特點和優勢

控释生物活性剂、缝线和可生物吸收植入器件。

外觀

具有生物相容性且可生物降解的聚合物。

法律資訊

Lactel is a registered trademark of Evonik Corp

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Eleftheria Babaliari et al.
International journal of molecular sciences, 19(7) (2018-07-18)
Cell responses depend on the stimuli received by the surrounding extracellular environment, which provides the cues required for adhesion, orientation, proliferation, and differentiation at the micro and the nano scales. In this study, discontinuous microcones on silicon (Si) and continuous
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
Mani Gajendiran et al.
Colloids and surfaces. B, Biointerfaces, 104, 107-115 (2013-01-10)
A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles

文章

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

條款

Biodegradable Nanoparticle

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務