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重要文件

P2191

Sigma-Aldrich

聚(D,L-丙交酯-co-乙交酯)

lactide:glycolide (50:50), mol wt 30,000-60,000

同義詞:

LACTEL® B6010-2, PLGA

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About This Item

線性公式:
[C3H4O2]x[C2H2O2]y
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.25

饋電比

lactide:glycolide (50:50)

分子量

30,000-60,000

儲存溫度

−20°C

SMILES 字串

OCC(O)=O.CC(O)C(O)=O

InChI 密鑰

XBBVURRQGJPTHH-UHFFFAOYSA-N

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一般說明

聚(D,L-丙交酯-共-乙交酯)是一种可生物降解的生物相容性聚合物,可用于药物输送。它可用于治疗类风湿性关节炎、溃疡性结肠炎、克罗恩病、炎性肺病、以及眼部炎性疾病。聚(D,L-丙交酯-共-乙交酯)可作为潜在的癌症治疗靶标起作用。

應用

聚(D,L-丙交酯-共-乙交酯)已经用于在凝胶中提高和维持乳酸盐单体水平,其浓度与皮肤伤口有关。

特點和優勢

控释生物活性剂、缝线和可生物吸收植入器件。

外觀

具有生物相容性且可生物降解的聚合物。

法律資訊

Lactel is a registered trademark of Evonik Corp

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms
Hunt TK, et al.
Antioxidants & Redox Signaling, 9(8), 1115-1124 (2007)
Characterization of biodegradable poly (D, L-lactide-co-glycolide) polymers and microspheres
Hausberger AG and DeLuca PP
Journal of Pharmaceutical and Biomedical Analysis, 13(6), 747-760 (1995)
Sultan A M Saghir et al.
Animals : an open access journal from MDPI, 9(11) (2019-11-14)
Pulmonary fibrosis is considered one of the most chronic interstitial illnesses which are not easily treated. thymoquinone's (TQ) benefits are still partly problematic due to poor water solubility; therefore, it was loaded onto PLGA-PVA carriers. This study aimed to evaluate
PLGA-based nanoparticles: an overview of biomedical applications
Danhier F, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 161(2), 505-522 (2012)
Habibun Nabi et al.
Parasitology research, 116(1), 359-370 (2016-10-28)
Toxoplasmosis is one of the most common zoonotic protozoal diseases. Recent advances in biotechnology have produced recombinant protein, which are immunogenic, and progress in nano-pharmaceutics has generated encapsulated protein in nanospheres, which are suitable for vaccine delivery. DNA was extracted

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