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739960

Resomer^® RG 505，聚（D,L-丙交酯-co-乙交酯）

Name: Resomer<SUP>®</SUP> RG 505，聚（<SC>D,L</SC>-丙交酯-<I>co</I>-乙交酯）
Brand: ALDRICH

ester terminated, M_w 54,000-69,000

同義詞:

PLGA, RESOMER^® RG 505

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About This Item

線性公式:

[C₃H₄O₂]_x[C₂H₂O₂]_y

CAS號碼:

26780-50-7

MDL號碼:

MFCD00131930

分類程式碼代碼:

12162002

NACRES:

NA.23

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形狀

amorphous

饋電比

lactide:glycolide 50:50

分子量

M_w 54,000-69,000

降解時間

<3 months

黏度

0.61-0.74 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

轉變溫度

T_g 48-52 °C

儲存溫度

2-8°C

SMILES 字串

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI 密鑰

LCSKNASZPVZHEG-UHFFFAOYSA-N

一般說明

聚（丙交酯-乙交酯）（PLGA）是一种可生物降解的聚合物，用于制备聚合物微球。这些聚合物在体内通过其酯骨架水解为无毒产物而降解，这些无毒产物可由肾脏排出，或通过生物化学途径分解为CO₂和水。PLGA微球被广泛应用于包裹药物分子，并可用作长效缓释药物制剂。

應用

聚（丙交酯-乙交酯）（PLGA）可用于制造缓释药物递送体系，例如，它可用于包裹抗炎亲脂药物阿托伐他汀。

法律資訊

Evonik产品

RESOMER is a registered trademark of Evonik Rohm GmbH

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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重要文件

Resomer^® RG 505，聚（D,L-丙交酯-co-乙交酯）