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Merck

T0682

Sigma-Aldrich

牛磺猪去氧胆酸钠 水合物

≥98%

别名:

牛磺猪去氧胆酸 钠盐 水合物

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About This Item

线性分子式:
C26H44NO6SNa · xH2O
CAS号:
分子量:
521.69 (anhydrous basis)
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.25

描述

anionic

品質等級

化驗

≥98%

分子量

521.69 g/mol (anhydrous basis)

應用

detection

SMILES 字串

O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C26H45NO6S.Na.H2O/c1-16(4-7-24(30)27-12-13-34(31,32)33)19-5-6-20-18-15-23(29)22-14-17(28)8-10-26(22,3)21(18)9-11-25(19,20)2;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18+,19-,20+,21+,22+,23+,25-,26-;;/m1../s1

InChI 密鑰

MJKUJELEPWZEGU-IGEKTTBWSA-M

一般說明

牛磺猪去氧胆酸钠水合物是牛磺酸酰胺化胆盐,可作为阴离子洗涤剂。

應用

牛磺猪去氧胆酸钠水合物已用于一项研究,以评估呋喃处理大鼠肝脏中细胞毒性、再生性细胞增殖和继发性氧化 DNA 损伤的剂量响应数据。 它也被用于一项研究,以探讨使用固定化人工膜 HPLC 柱预测胆盐-膜相互作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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K J Van Erpecum et al.
European journal of clinical investigation, 26(7), 602-608 (1996-07-01)
Precipitation of cholesterol crystals is an essential step in gallstone formation. In the present study we found much faster and more extensive precipitation of various cholesterol crystal shapes in whole model biles containing the hydrophobic bile salt taurodeoxycholate than in
Francesca Carubbi et al.
Biochimica et biophysica acta, 1580(1), 31-39 (2002-03-30)
This study was performed to compare the effects of two hydrophilic bile acids, taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA), on HepG2 cells. Cytotoxicity was evaluated at different times of exposure by incubating cells with increasing concentrations (50-800 micromol/l) of
P Loria et al.
Hepatology (Baltimore, Md.), 25(6), 1306-1314 (1997-06-01)
This study aimed to determine the effect in humans of taurohyodeoxycholic acid, a 6alpha-hydroxylated bile acid with hydrophilic properties, on bile lipid secretion. Four cholecystectomized patients who had gallstones and an interrupted enterohepatic circulation were intraduodenally infused with taurohyodeoxycholic and
F Feletti et al.
Arzneimittel-Forschung, 43(8), 894-897 (1993-08-01)
The reproductive toxicity of taurohyodeoxycholic acid (3 alpha, 6 alpha-dihydroxy-5-beta-cholanoyl-2-amino-ethyl-sulfonic acid, THDCA, Io, Praxis, CAS 2958-04-5), a new synthetized biliary acid patented in Europe, Japan and the United States for prevention and therapy of gallstones and related symptoms, was assayed
M Paolini et al.
Hepatology (Baltimore, Md.), 30(3), 730-739 (1999-08-26)
We examined the effects of the administration of different bile acids on in vivo hepatic murine cytochrome P450 (CYP) content, nicotinamide adenine dinucleotide phosphate (NADPH)-CYP-reductase, and individual mixed-function oxidases (MFOs). Neither CYP level nor reductase were appreciably affected by single

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