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T6260

Sigma-Aldrich

牛磺鹅去氧胆酸钠

别名:

2-（[3α,7α-二羟基-24-氧代-5β-胆烷-24-基] 氨基）乙磺酸 钠盐, 3α,7α-二羟基-5β-胆烷-24-酸 N-（2-磺乙基）酰胺 钠盐, 牛磺鹅脱氧胆酸 钠盐

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About This Item

经验公式（希尔记法）:
C26H44NNaO6S
CAS号:
6009-98-9
分子量:
521.69
Beilstein:
3901205
MDL號碼:
MFCD00036745
分類程式碼代碼:
41141802
PubChem物質ID:
24900362
NACRES:
NA.25

描述

anionic

品質等級

200

化驗

≥95.0% (TLC)

形狀

powder

分子量

521.69 g/mol

CMC

4

HLB

20.1

官能基

sulfonic acid

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

[H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCCS(=O)([O-])=O)=O.[Na+]

InChI

1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22-,24?,25+,26-;/m1./s1

InChI 密鑰

IYPNVUSIMGAJFC-ULWOGUKGSA-M

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相关类别

一般說明

一种离子洗涤剂，用于溶解脂肪和蛋白质。
牛磺鹅去氧胆酸钠是一种胆汁酸，可用作阴离子洗涤剂。

應用

牛磺鹅去氧胆酸钠已用于一项研究，以评估胰岛 β-细胞有助于 BA 依赖的葡萄糖调节。 也被用于研究胆汁酸盐 在体内对牛磺胆酸钠共转运多肽 (Ntcp) 的短期反馈调节 。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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Noritaka Kawasaki et al.
Scientific reports, 2, 799-799 (2012-11-15)
Adipose tissue plays a central role in maintaining metabolic homeostasis under normal conditions. Metabolic diseases such as obesity and type 2 diabetes are often accompanied by chronic inflammation and adipose tissue dysfunction. In this study, we observed that endoplasmic reticulum
Rohit Kohli et al.
Endocrinology, 154(7), 2341-2351 (2013-04-18)
Bariatric surgery elevates serum bile acids. Conjugated bile acid administration, such as tauroursodeoxycholic acid (TUDCA), improves insulin sensitivity, whereas short-circuiting bile acid circulation through ileal interposition surgery in rats raises TUDCA levels. We hypothesized that bariatric surgery outcomes could be
M B Jiménez-Castro et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 12(12), 3257-3271 (2012-09-22)
Numerous steatotic livers are discarded for transplantation because of their poor tolerance to ischemia-reperfusion (I/R). We examined whether tauroursodeoxycholic acid (TUDCA), a known inhibitor of endoplasmic reticulum (ER) stress, protects steatotic and nonsteatotic liver grafts preserved during 6 h in
Colin N Young et al.
The Journal of clinical investigation, 122(11), 3960-3964 (2012-10-16)
Although endoplasmic reticulum (ER) stress is a pathologic mechanism in a variety of chronic diseases, it is unclear what role it plays in chronic hypertension (HTN). Dysregulation of brain mechanisms controlling arterial pressure is strongly implicated in HTN, particularly in
Kalaimathi Govindarajan et al.
PloS one, 11(12), e0167319-e0167319 (2016-12-03)
Disruptions to circadian rhythm in mice and humans have been associated with an increased risk of obesity and metabolic syndrome. The gut microbiota is known to be essential for the maintenance of circadian rhythm in the host suggesting a role
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