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生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
L5, monoclonal
物種活性
bovine, mouse, human, rat, guinea pig
製造商／商標名
Chemicon®
技術
western blot: suitable
同型
IgG2b
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... GNAI2(2771)
特異性
Gialpha-2. Strong reactivity with bovine (100%), mouse (69%), rat (69%), human (62%) and guinea pig (43%). Specificity confirmed by Western blot versus bovine Galphat, rat Goalpha, rat Gialpha-1, Gialpha-2, rat Gialpha-3, bovine Gsalpha, and murine GoalphaA and GoalphaB.
免疫原
Recombinant Gialpha-2, purified by the method of Linder (1990).
應用
Anti-G Protein Giα-2 Antibody, clone L5 is an antibody against G Protein Giα-2 for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
GPCR, cAMP/cGMP & Calcium Signaling
Western blot 1:500 - 1:1000, with detection by 125I-labeled anti-IgG.
Labels a single protein band of 39 - 42 kDa in bovine and rat membranes.
Optimal working dilutions must be determined by end user.
Labels a single protein band of 39 - 42 kDa in bovine and rat membranes.
Optimal working dilutions must be determined by end user.
外觀
Format: Purified
Purified immunoglobulin, in 0.02M phosphate buffer, 0.25M sodium chloride, pH 7.6, with 0.1% sodium azide.
儲存和穩定性
Maintain at 2-8°C.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Chronic but not acute intracerebroventricular administration of amyloid beta-peptide(25-35) decreases somatostatin content, adenylate cyclase activity, somatostatin-induced inhibition of adenylate cyclase activity, and adenylate cyclase I levels in the rat hippocampus.
E Burgos-Ramos,A Hervas-Aguilar,L Puebla-Jimenez,M C Boyano-Adanez,E Arilla-Ferreiro
Journal of Neuroscience Research null
Hiromi Ohara et al.
The Journal of veterinary medical science, 75(1), 85-88 (2012-08-11)
In rodents, Gα(i2)-expressing sensory neurons (SNs) that co-express vomeronasal receptor type 1 (V1R) are specifically found in the vomeronasal organ (VNO) and project their axons to the accessory olfactory bulb (AOB). In goats, however, Gα(i2)/V1R-expressing SNs exist in both the
Kati S Mönkkönen et al.
Human reproduction (Oxford, England), 22(5), 1224-1230 (2007-03-10)
Heterotrimeric G proteins take part in membrane-mediated cell signalling and have a role in hormonal regulation. This study clarifies the expression and localization of the G protein subunit G alpha(i2) in the human endometrium and Fallopian tube and changes in
J T O'Flaherty et al.
Journal of immunology (Baltimore, Md. : 1950), 164(6), 3345-3352 (2000-03-08)
5-Oxo-eicosatetraenoic acid (5-oxoETE) stimulated human neutrophil (PMN) and eosinophil chemotaxis, PMN hexose uptake, and PMN membrane GTP/GDP exchange. Pertussis toxin (PT), a blocker of heterotrimeric G proteins (GP), completely inhibited these responses, but proved far less effective on the same
Activity of the hippocampal somatostatinergic system following daily administration of melatonin.
Rosa Maria Izquierdo-Claros, Maria Del Carmen Boyano-Adanez, Eduardo Arilla-Ferreiro
Brain Research Molecular Brain Research null
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