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Key Documents

M3183

Sigma-Aldrich

MOPS

≥99.5% (titration), crystalline powder, BioPerformance Certified, suitable for cell culture

Synonym(s):

3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H15NO4S
CAS Number:
Molecular Weight:
209.26
Beilstein/REAXYS Number:
1106776
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

product name

MOPS, BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

grade

BioPerformance Certified

Quality Level

assay

≥99.5% (titration)

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and TAMC, tested

pH

2.5-4 (25 °C, 209 g/L)

useful pH range

6.5-7.9

pKa (25 °C)

7.2

cation traces

Fe: ≤5 ppm

λ

33 % in H2O

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, protease, none detected

SMILES string

OS(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

InChI key

DVLFYONBTKHTER-UHFFFAOYSA-N

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Application


  • A production platform for disulfide-bonded peptides in the periplasm of Escherichia coli.: This research developed a novel platform for producing disulfide-bonded peptides in E. coli, using MOPS buffer to maintain a stable pH environment essential for protein folding and stability in the periplasmic space. The platform could significantly enhance the production of therapeutically relevant peptides (Gibisch et al., 2024).


Packaging

M3183-1KT:
Each kit contains 3 x 100G samples, each sample from a uniquely manufactured lot.

Other Notes

Easily compare specifications for MOPS products with the MOPS specification table.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Junji Suzuki et al.
Nature communications, 5, 4153-4153 (2014-06-14)
The endoplasmic reticulum (ER) and mitochondria accumulate Ca(2+) within their lumens to regulate numerous cell functions. However, determining the dynamics of intraorganellar Ca(2+) has proven to be difficult. Here we describe a family of genetically encoded Ca(2+) indicators, named calcium-measuring
Y S L Lee et al.
Human reproduction (Oxford, England), 30(3), 543-552 (2015-01-09)
What is the relationship between cleavage stage embryo kinetics, blastocyst metabolism and subsequent embryo viability? Embryos cleaving faster at the first cleavage division resulted in blastocysts with a larger inner cell mass (ICM), higher glucose consumption, lower glycolytic rate, higher
Sewa Rijal et al.
Blood, 125(18), 2815-2824 (2015-03-05)
Phosphoinositide signaling regulates diverse cellular functions. Phosphoinositide-3 kinase (PI3K) generates PtdIns(3,4,5)P3 and PtdIns(3,4)P2, leading to the activation of proliferative and anti-apoptotic signaling pathways. Termination of phosphoinositide signaling requires hydrolysis of inositol ring phosphate groups through the actions of PtdIns(3,4,5)P3 3-phosphatase
Sanna Byström et al.
Journal of proteome research, 13(11), 4607-4619 (2014-09-19)
The brain is a vital organ and because it is well shielded from the outside environment, possibilities for noninvasive analysis are often limited. Instead, fluids taken from the spinal cord or circulatory system are preferred sources for the discovery of
Alexandre Albanese et al.
ACS nano, 8(6), 5515-5526 (2014-05-07)
A nanoparticle's physical and chemical properties at the time of cell contact will determine the ensuing cellular response. Aggregation and the formation of a protein corona in the extracellular environment will alter nanoparticle size, shape, and surface properties, giving it

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