ALD00604
(+)-PSI Reagent
95%
Synonym(s):
(+)-Ψ, (2R,3aR,6S,7aR)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide, Phosphorus-Sulfur Incorporation Reagent
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About This Item
Empirical Formula (Hill Notation):
C16H16F5OPS3
CAS Number:
Molecular Weight:
446.46
UNSPSC Code:
12352101
NACRES:
NA.22
assay
95%
form
powder or crystals
mp
102-107 °C
Application
Air- and moisture-tolerant, this (+)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (−)-PSI Reagent, is also available (cat# ALD00602).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
Learn more about PI and PSI reagents
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
Learn more about PI and PSI reagents
Legal Information
PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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