73594

Ammonium acetate

LiChropur^™, eluent additive for LC-MS

• Linear Formula: CH₃CO₂NH₄
• CAS Number: 631-61-8
• Molecular Weight: 77.08
• Beilstein/REAXYS Number: 4186741
• EC Number: 211-162-9
• MDL number: MFCD00013066
• UNSPSC Code: 12000000
• eCl@ss: 39021908
• PubChem Substance ID: 329765068
• NACRES: NB.21

Properties

• grade: eluent additive for LC-MS
• Quality Level: 100
• agency: suitable for ASTM^® 7968; suitable for ASTM^® 7979; suitable for DIN 38407-42; suitable for EPA 1633; suitable for EPA 533; suitable for EPA 537.1; suitable for EPA 8327; suitable for EPA ACB B21-02; suitable for EPA ACB B23-05b; suitable for GB 31604.35-2016; suitable for GB 5009.253-2016; suitable for ISO 21675 2019; suitable for ISO 25101; suitable for ISO/CEN 15968-2010
• reg. compliance: suitable for FDA C-010.02
• assay: ≥99.0% (calc. on dry substance, T)
• form: solid
• quality: LiChropur^™
• technique(s): LC/MS: suitable
• impurities: insoluble matter, passes filter test; ≤1% water
• ign. residue: ≤0.01% (as SO₄)
• pH: 6.2-7.5 (25 °C, 1 M in H₂O)
• mp: 110-112 °C (dec.) (lit.)
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤5 mg/kg; nitrate (NO₃^-): ≤10 mg/kg; sulfate (SO₄^2-): ≤10 mg/kg
• cation traces: Al: ≤1 mg/kg; As: ≤0.1 mg/kg; Ba: ≤1 mg/kg; Bi: ≤1 mg/kg; Ca: ≤5 mg/kg; Cd: ≤1 mg/kg; Co: ≤1 mg/kg; Cr: ≤1 mg/kg; Cu: ≤1 mg/kg; Fe: ≤1 mg/kg; K: ≤5 mg/kg; Li: ≤1 mg/kg; Mg: ≤1 mg/kg; Mn: ≤1 mg/kg; Mo: ≤1 mg/kg; Na: ≤5 mg/kg; Ni: ≤1 mg/kg; Pb: ≤1 mg/kg; Sr: ≤1 mg/kg; Zn: ≤1 mg/kg
• SMILES string: N.CC(O)=O
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: ≤0.015; λ: 280 nm A_max: ≤0.010
• suitability: passes test for LC-MS
• InChI: 1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3
• InChI key: USFZMSVCRYTOJT-UHFFFAOYSA-N

Description

General description

Ammonium acetate exists as a white crystal. It is prepared from acetic acid and ammonia by neutralization to pH 7.0. It is widely used in analytical chemistry, drugs and in textile dyeing.

Application

Ammonium acetate has been used to prepare eluents for UPLC-MS/MS and HPLC-MS/MS to compare the matrix effect of 9 pharmaceutical compounds in aqueous environmental samples. It has also been used as an additive to improve detection of phosphopeptides using MALDI-MS.

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Legal Information

ASTM is a registered trademark of American Society for Testing and Materials

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)