50058
Glycine
100.0%, tested according to Ph. Eur.
Synonym(s):
Glycinum, Aminoacetic acid, Aminoethanoic acid, Glycocoll
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product name
Glycine, tested according to Ph. Eur.
agency
USP/NF
tested according to Ph. Eur.
Quality Level
assay
100.0%
form
crystalline
color
white
pH
6.2
pKa (25 °C)
(1) 2.35, (2) 9.60
2.35
mp
240 °C (dec.) (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
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Biochem/physiol Actions
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
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The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
The EMBO journal, 32(24), 3220-3230 (2013-11-12)
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 278-282 (2006-08-08)
A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in
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The zebrafish is emerging as a popular animal model for alcohol (ethanol or EtOH) addiction due to its simplicity and practical advantages. Two phenomena associated with ethanol addiction are the development of tolerance and withdrawal. Using a multi-level approach in
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