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10108294001

Roche

Phosphoenol-pyruvate

97% (PEP-K), pkg of 1 g

Synonym(s):

Phospho(enol)pyruvic acid monopotassium salt, 2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K

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About This Item

Empirical Formula (Hill Notation):
C3H4KO6P
CAS Number:
4265-07-0
Molecular Weight:
206.13
Beilstein/REAXYS Number:
4603446
MDL number:
MFCD00044476
UNSPSC Code:
12352204
PubChem Substance ID:
329748896

description

C3H4O6PK (Formula)
PEP, monopotassium salt

Quality Level

100

assay

97% (PEP-K)

form

solid

mol wt

Mr 168.0 (PEP)
Mr 206.1 (PEP-K)

packaging

pkg of 1 g

manufacturer/tradename

Roche

storage temp.

2-8°C

SMILES string

[K+].OC(=O)C(=C)OP(O)([O-])=O

InChI

1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1

InChI key

SOSDSEAIODNVPX-UHFFFAOYSA-M

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General description

Contents: 80% PEP (enzymatic)

Application

Phosphoenolpyruvate (PEP) has been used in:
  • glutamate-cysteine ligase activity
  • v-ATPase enzyme activity assay
  • meso kinase assay

Substrate for pyruvate kinase.

Biochem/physiol Actions

Phosphoenolpyruvate (PEP) plays a vital role in metabolism. It has a high phosphate group-transfer potential and it serves a versatile C3-synthon in C–C, C–P and C–O bond-formation reactions. PEP acts as a substrate for pyruvate kinase (PK) in the last step of glycolysis.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes.
Garcia A, et al.
FEBS Journal, 269(13), 3226-3236 (2002)
Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells.
Desideri E
Autophagy, 8(12), 1769-1781 (2012)
Maria B Bagh et al.
Nature communications, 8, 14612-14612 (2017-03-08)
Defective lysosomal acidification contributes to virtually all lysosomal storage disorders (LSDs) and to common neurodegenerative diseases like Alzheimer's and Parkinson's. Despite its fundamental importance, the mechanism(s) underlying this defect remains unclear. The v-ATPase, a multisubunit protein complex composed of cytosolic
Jasmine M Hershewe et al.
Nature communications, 12(1), 2363-2363 (2021-04-24)
Cell-free gene expression (CFE) systems from crude cellular extracts have attracted much attention for biomanufacturing and synthetic biology. However, activating membrane-dependent functionality of cell-derived vesicles in bacterial CFE systems has been limited. Here, we address this limitation by characterizing native
Trace Thome et al.
American journal of physiology. Cell physiology, 317(4), C701-C713 (2019-07-11)
Chronic kidney disease (CKD) leads to increased skeletal muscle fatigue, weakness, and atrophy. Previous work has implicated mitochondria within the skeletal muscle as a mediator of muscle dysfunction in CKD; however, the mechanisms underlying mitochondrial dysfunction in CKD are not
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