TX1568

Triton^™ X-100

Non-ionic detergent and emulsifier

• Synonym(s): Triton^™ X-100, Octylphenol Decaethylene Glycol Ether, t-Octylphenoxypolyethoxyethanol, Polyethylene glycol tert-octylphenyl ether
• Linear Formula: t-Oct-C₆H₄-(OCH₂CH₂)_xOH, x= 9-10
• CAS Number: 9036-19-5
• Beilstein/REAXYS Number: 2315025
• MDL number: MFCD00128254
• UNSPSC Code: 12161902

Properties

• product name: Triton^™ X-100 Surfactant,
• form: viscous liquid
• Quality Level: 200
• mol wt: micellar avg mol wt 80,000; average mol wt 625
• aggregation number: 100-155
• color: APHA: ≤150
• CMC: 0.2-0.9 mM (20-25°C)
• mp: 6 °C
• transition temp: flash point 251 °C; cloud point 65 °C; pour point ~7 °C
• HLB: 13.5
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1
• InChI: 1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3
• InChI key: HNLXNOZHXNSSPN-UHFFFAOYSA-N

Description

Application

• Identification of protein components of the transformation system in the cell line of immortalized human keratinocytes HaCaT exposed to surfactants.: This study utilizes Triton^™ X-100 Surfactant to identify protein components in immortalized human keratinocytes. The research highlights the surfactant′s role in cell transformation systems and its impact on protein composition, providing insights into cellular response mechanisms. (Shkrigunov et al., 2024).


• In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.: This study presents a method using Triton^™ X-100 Surfactant for isolating nuclei or nuclear proteins from adherent cells. The findings demonstrate reduced cytoplasmic contamination, enhancing the accuracy of nuclear protein studies. (Qin et al., 2023).


• Inter-Regional Proteomic Profiling of the Human Brain Using an Optimized Protein Extraction Method from Formalin-Fixed Tissue to Identify Signaling Pathways.: This research employs Triton^™ X-100 Surfactant in an optimized protein extraction method for proteomic profiling of the human brain. The study identifies critical signaling pathways, underscoring the surfactant′s utility in neuroscience research. (Davidson et al., 2023).

Biochem/physiol Actions

Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.

Analysis Note

Acidity (as Na2O)%Alkalinity (as Na2O)%Cloud point (1%, water)63-69°CColor (APHA)150 maxFormClear, viscous liquidSpecific Gravity at 25/25°C1.063-1.067pH of a 1% aqueous solution5-8

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

Safety Information

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H315,H318,H410
• pcodes: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 483.8 °F - closed cup
• flash_point_c: 251 °C - closed cup