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900863

Sigma-Aldrich

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

≥95%

Synonym(s):

3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol, Hydroxyl diazirine alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):
C7H10N2O
CAS Number:
Molecular Weight:
138.17
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22

Quality Level

assay

≥95%

form

liquid

density

1.08 g/mL

storage temp.

−20°C

SMILES string

OCCC1(N=N1)CCC#C

Application

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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Pricing

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Articles

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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