708631

Quinoxaline-6-boronic acid pinacol ester

97%

• Empirical Formula (Hill Notation): C₁₄H₁₇BN₂O₂
• CAS Number: 1167418-13-4
• Molecular Weight: 256.11
• MDL number: MFCD11054040
• UNSPSC Code: 12352103
• PubChem Substance ID: 329762815
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.560
• density: 1.123 g/mL at 25 °C
• SMILES string: CC1(C)OB(OC1(C)C)c2ccc3nccnc3c2
• InChI: 1S/C14H17BN2O2/c1-13(2)14(3,4)19-15(18-13)10-5-6-11-12(9-10)17-8-7-16-11/h5-9H,1-4H3
• InChI key: ZYWICCYXTGRUNM-UHFFFAOYSA-N

Description

Application

Quinoxaline-6-boronic acid pinacol ester is a common reactant of a Suzuki coupling reaction that can be used:

• To prepare quinoxalin based PI3Kδ inhibitors.
• As a substrate in the Cu(II) catalyzed [¹¹C]-radiocyanation of arylboronic acids.
• To prepare 6-quinoxaline boronic acid, which is used as a substrate in the silver-mediated fluorination of boronic acids.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: >230.0 °F
• flash_point_c: > 110 °C