260789
8-Aminoquinoline
98%
Synonym(s):
8-Quinolinamine
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About This Item
Empirical Formula (Hill Notation):
C9H8N2
CAS Number:
Molecular Weight:
144.17
Beilstein/REAXYS Number:
114474
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
98%
form
solid
reaction suitability
reaction type: C-H Activation
reagent type: catalyst
bp
174 °C/26 mmHg (lit.)
mp
60-65 °C (lit.)
SMILES string
Nc1cccc2cccnc12
InChI
1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
InChI key
WREVVZMUNPAPOV-UHFFFAOYSA-N
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General description
8-Aminoquinoline fluoresce moderately to weakly in low dielectric media but not in strongly hydrogen-bonding or acidic aqueous media. The reaction of 8-aminoquinoline with chromium (III), manganese (II), iron (II) and (III), cobalt (II), nickel (II), copper (II), zinc (II), cadmium (II) and platinum (II) salts has been studied.
Application
8-Aminoquinoline has been used in:
- preparation of base-stabilized terminal borylene complex of osmium
- spectrophotometric determination of bivalent palladium
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Xiaowei Cao et al.
Organic letters, 13(17), 4716-4719 (2011-08-04)
The first NIR fluorescent sensor for sulfide anions was constructed based on the displacement approach. The sensing ensemble is composed of a cyanine dye, a piperazine linker, an 8-aminoquinoline ligand, and copper. The favorable attributes of the sensor include a
Zhipeng Liu et al.
Organic letters, 14(17), 4378-4381 (2012-08-14)
A new ratiometric fluorescent sensor for Cu(2+), WLN, has been developed via integrating a 1,8-naphthalimide fluorophore with 8-aminoquinoline. WLN exhibits a highly selective ratiometric response to Cu(2+) over other transition metal ions in aqueous media. Moreover, its practical ratiometric imaging
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The surge in interest in switching from traditionally used wet plasma to dried matrix spot (DMS) sampling and analysis to support pharmaceutical drug development is due to the significant ethical, financial and data quality advantages on offer. Unfortunately these advantages
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Palladium(II) complexes are potential antitumor metallodrugs for their chemical resemblance to platinum(II) complexes. Two palladium(II) complexes (1 and 2) in the formula of [PdL(n)Cl] [L(1) = N-(tert-butoxycarbonyl)-l-methionine-N'-8-quinolylamide, L(2) = L-alanine-N'-8-quinolylamide] have been synthesized accordingly. The structures of the complexes were
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