1463960

Nitazoxanide

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): NTZ; 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide
• Wzór empiryczny (zapis Hilla): C₁₂H₉N₃O₅S
• Numer CAS: 55981-09-4
• Masa cząsteczkowa: 307.28
• Numer MDL: MFCD00416599
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329750564
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• rodzina API: nitazoxanide
• producent / nazwa handlowa: USP
• Zastosowanie: pharmaceutical (small molecule)
• Format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: CC(=O)Oc1ccccc1C(=O)Nc2ncc(s2)[N+]([O-])=O
• InChI: 1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)
• Klucz InChI: YQNQNVDNTFHQSW-UHFFFAOYSA-N

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Nitazoxanide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Działania biochem./fizjol.

Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); Antimicrobial recently found to kill both non-replicating and replicating mycobacteria.

Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); FDA approved anti-parasitic drug (2002). Recent work (C & EN Sept. 14, 2009, p. 28) highlights that NTZ kills non-replicating and replicating TB bacteria and no apparent resistance is detected.

Komentarz do analizy

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Inne uwagi

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable