BP1234

Letrozole

British Pharmacopoeia (BP) Reference Standard

• Synonim(y): 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
• Wzór empiryczny (zapis Hilla): C₁₇H₁₁N₅
• Numer CAS: 112809-51-5
• Masa cząsteczkowa: 285.30
• Numer MDL: MFCD00866241
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• Poziom jakości: 100
• rodzina API: letrozole
• Postać: powder
• okres trwałości: limited shelf life, expiry date on the label
• producent / nazwa handlowa: BP
• Zastosowanie: pharmaceutical; pharmaceutical small molecule
• format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: N#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
• InChI: 1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
• Klucz InChI: HPJKCIUCZWXJDR-UHFFFAOYSA-N
• informacje o genach: human ... CYP19A1(1588)

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Letrozole BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Letrozole Tablets

Działania biochem./fizjol.

Letrozole is a third generation nonsteroidal aromatase inhibitor. It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the conversion of androgens to estrogens. Letrozole inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.

Opakowanie

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Inne uwagi

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H361fd,H373
• Zwroty wskazujące środki ostrożności: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Klasyfikacja zagrożeń: Repr. 2 - STOT RE 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable